SCHEMBL18174675

SCHEMBL18174675

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ncccc5C)cc4)c4ccccc34)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.50
TRPV1 Q8NER1 4/20 0.39
CNR2 P34972 1/20 0.38
PDK1 Q15118 4/20 0.36
METAP2 P50579 1/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
DHODH Q02127 1/20 0.34
GBA1 P04062 1/20 0.34
PDE10A Q9Y233 1/20 0.34
PSMB5 P28074 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174742 0.93 CYP2A6 (0.49) CYP2A6TRPV1CNR2CYP11B1CYP11B2
SCHEMBL18174567 0.84 CYP2A6 (0.53) CYP2A6TRPV1CNR2PDK1METAP2
SCHEMBL15161112 0.84 CYP2A6 (0.47) CYP2A6CYP11B1CYP11B2GBA1PSMB5
SCHEMBL15160972 0.82 CYP2A6 (0.46) CYP2A6CYP11B1CYP11B2DHODH
SCHEMBL18174747 0.82 CYP2A6 (0.46) CYP2A6CYP11B1CYP11B2DHODHGBA1
SCHEMBL18174700 0.82 DHODH (0.44) CYP2A6METAP2CYP11B1CYP11B2DHODH
SCHEMBL15160977 0.81 CYP2A6 (0.44) CYP2A6CYP11B1CYP11B2DHODH
SCHEMBL18174697 0.81 CYP2A6 (0.47) CYP2A6TRPV1CNR2PDK1METAP2
SCHEMBL18174698 0.81 GPR55 (0.40) CYP2A6CYP11B1CYP11B2GBA1PSMB5
SCHEMBL15977631 0.80 CYP2A6 (0.46) CYP2A6TRPV1CNR2PDK1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed