SCHEMBL18174699

SCHEMBL18174699

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc(C)nc5)cc4)c4ccccc34)cc2)nc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
CYP2A6 P11509 1/20 0.46
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
PKM P14618 1/20 0.35
KDM1A O60341 1/20 0.35
PIM1 P11309 1/20 0.34
METAP2 P50579 1/20 0.34
HPGDS O60760 2/20 0.34
ACHE P22303 1/20 0.34
PDK2 Q15119 1/20 0.34
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161072 0.91 CYP3A4 (0.44) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174561 0.89 CCR1 (0.54) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL17051523 0.87 CCR1 (0.56) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL17532877 0.86 NPC1 (0.44) CYP2A6NPC1RAB9APKMHPGDS
SCHEMBL16189029 0.84 CYP3A4 (0.42) CYP3A4CYP2A6NPC1RAB9APKM
SCHEMBL18174690 0.84 CYP2A6 (0.44) CYP2A6CCR1CCR5CCR8NPC1
SCHEMBL18174692 0.82 DYRK1A (0.43) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL15977627 0.81 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL15161016 0.81 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174644 0.81 CYP3A4 (0.45) CYP3A4CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed