SCHEMBL18174725

SCHEMBL18174725

Cc1cnccc1-c1ccc(-c2c3ccccc3c(-c3cccc(-c4ncccc4C)c3)c3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.49
GRM4 Q14833 1/20 0.36
CYP17A1 P05093 2/20 0.36
CYP1A2 P05177 2/20 0.36
PIK3CA P42336 1/20 0.36
CYP19A1 P11511 1/20 0.36
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 1/20 0.35
CNR2 P34972 1/20 0.35
PTGS2 P35354 1/20 0.35
BRD4 O60885 1/20 0.34
SQOR Q9Y6N5 3/20 0.34
DYRK1A Q13627 2/20 0.34
DYRK1B Q9Y463 1/20 0.34
GPBAR1 Q8TDU6 1/20 0.34
ABL1 P00519 1/20 0.34
CHEK1 O14757 1/20 0.34
RPS6KA5 O75582 1/20 0.34
MAP4K4 O95819 1/20 0.34
PRKCG P05129 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174649 0.91 CYP2A6 (0.51) CYP2A6GRM4CYP17A1CYP1A2CYP19A1
SCHEMBL15161094 0.91 CYP2A6 (0.49) CYP2A6CYP17A1CYP1A2PTGS2DYRK1A
SCHEMBL18174750 0.87 GRM4 (0.43) GRM4CYP17A1CYP1A2CYP19A1S1PR1
SCHEMBL18174755 0.86 DHODH (0.41) GRM4CYP17A1CYP1A2PIK3CACYP19A1
SCHEMBL18174716 0.85 PIK3CA (0.47) CYP2A6GRM4CYP17A1CYP1A2PIK3CA
SCHEMBL18174566 0.84 CYP2A6 (0.53) CYP2A6CNR2BRD4ABL1
SCHEMBL18174713 0.84 PIK3CA (0.41) GRM4CYP17A1CYP1A2PIK3CACYP19A1
SCHEMBL18174729 0.84 CYP2A6 (0.42) CYP2A6GRM4CYP17A1CYP1A2CYP19A1
SCHEMBL18174753 0.84 PIK3CA (0.45) GRM4CYP17A1CYP1A2PIK3CACYP19A1
SCHEMBL15161102 0.83 GRM4 (0.46) GRM4CYP17A1CYP1A2PIK3CACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed