SCHEMBL18174739

SCHEMBL18174739

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4cccc(-c5cccnc5C)c4)c4ccccc34)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.39
DHODH Q02127 1/20 0.38
MAPK10 P53779 1/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
METAP2 P50579 1/20 0.34
ENPP1 P22413 1/20 0.34
ABL1 P00519 1/20 0.34
ELANE P08246 1/20 0.34
S1PR1 P21453 1/20 0.33
CYP2A6 P11509 1/20 0.33
NPY5R Q15761 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174700 0.93 DHODH (0.44) APLNRDHODHMKNK1MKNK2PRMT5
SCHEMBL18174751 0.87 DHODH (0.39) APLNRDHODHMAPK10MKNK1MKNK2
SCHEMBL15161047 0.85 CYP11B2 (0.43) MKNK1MKNK2PRMT5WDR77CYP11B1
SCHEMBL18174565 0.84 DHODH (0.45) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL18174765 0.84 DHODH (0.44) APLNRDHODHMKNK1MKNK2PRMT5
SCHEMBL15161063 0.84 PIK3CA (0.43) DHODHMKNK1MKNK2PTGS1PTGS2
SCHEMBL18174744 0.84 DHODH (0.40) DHODHMAPK10MKNK1MKNK2PRMT5
SCHEMBL18174740 0.84 MKNK1 (0.45) DHODHMKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174742 0.83 CYP2A6 (0.49) MKNK1MKNK2PTGS1PTGS2CYP11B1
SCHEMBL18174723 0.83 CYP2A6 (0.43) CYP11B1CYP11B2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed