Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19721401 | 0.84 | GRM4 (0.49) | MAOAMAOBGRM4CCNCCDK8 | |
| SCHEMBL3423341 | 0.81 | CCNC (0.50) | MAOAMAOBGRM4CCNCCDK8 | |
| SCHEMBL29068840 | 0.77 | MAOA (0.47) | MAOAMAOBIDO1LIMK1GPBAR1 | |
| SCHEMBL946983 | 0.77 | TSHR (0.45) | MAOBIDO1CYP1A2METAP2 | |
| SCHEMBL29191166 | 0.76 | IDO1 (0.46) | MAOAMAOBIDO1LIMK1GPBAR1 | |
| SCHEMBL21034043 | 0.74 | TNF (0.50) | GRM4CYP19A1PDE2APDE10ACYP1A2 | |
| SCHEMBL31258556 | 0.74 | GRM4 (0.60) | GRM4CCNCCDK8CYP19A1TRPA1 | |
| SCHEMBL9169968 | 0.74 | GRM4 (0.60) | GRM4CCNCCDK8CYP19A1TRPA1 | |
| SCHEMBL19059572 | 0.73 | CYP17A1 (0.46) | GRM4CCNCCDK8CYP1A2 | |
| SCHEMBL2643285 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9478758-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-10-25 | — | — | US | disclosed |