SCHEMBL946983

SCHEMBL946983

Cc1ccccc1-c1ccccc1S

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
ACHE P22303 2/20 0.45
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
BRD4 O60885 1/20 0.39
HTR7 P34969 1/20 0.38
IDO1 P14902 2/20 0.38
GAA P10253 1/20 0.38
METAP2 P50579 1/20 0.38
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23891346 0.83 CA12 (0.50) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL15259433 0.83 TRPA1 (0.39) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL5890645 0.83 TSHR (0.39) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL30354037 0.83 ACHE (0.64) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL30169568 0.83 ACHE (0.64) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL197690 0.83 ACHE (0.64) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL331374 0.83 MEN1 (0.47) TSHRNPC1RAB9ASMN1; SMN2CASP3
SCHEMBL27565196 0.81 NPC1 (0.38) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL5887692 0.80 MYC (0.48) TSHRACHENPC1RAB9ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL842431 0.80 ACHE (0.60) TSHRACHENPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120054633-A Catalyst containing sulfur phosphite ligand and preparation method of hexamethylene dinitrile 北京旭阳科技有限公司 2025-05-30 CN claimed
CN-118852506-A Triplet state energy transfer induced polymerization photocatalyst and preparation method and application thereof 华东理工大学 2024-10-29 CN claimed
CN-117899093-A Pharmaceutical use of 4-tolylthiophenol diphenyl-2-pyridinium phosphine alloy (I) 电子科技大学 2024-04-19 CN claimed
CN-116284169-A Synthesis method of N-acetyl-D-lactosamine 四川轻化工大学 2023-06-23 CN claimed
CN-114609263-A Detection method of (R) -2, 4-diiodo-3-methyl-1-alkene and enantiomer thereof 苏州正济药业有限公司 2022-06-10 CN claimed
CN-112759678-A Catalyst component for olefin polymerization, preparation method thereof, catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-108425104-B Preparation method of coating taking mercapto compound as transition layer 江苏菲沃泰纳米科技有限公司 2020-02-18 CN claimed
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
CN-120054633-A Catalyst containing sulfur phosphite ligand and preparation method of hexamethylene dinitrile 北京旭阳科技有限公司 2025-05-30 CN disclosed
CN-118852506-A Triplet state energy transfer induced polymerization photocatalyst and preparation method and application thereof 华东理工大学 2024-10-29 CN disclosed
CN-118591301-A Method for inhibiting odor of p-cresol 味之素株式会社 2024-09-03 CN disclosed
CN-114609263-B Method for detecting (R) -2, 4-diiodo-3-methyl-1-alkene and enantiomer thereof 苏州正济药业有限公司 2024-06-18 CN disclosed
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing SAN-APRO LIMITED (JP) 2006-11-02 US disclosed
US-7112697-B1 Methods for formation of aryl-sulfur and aryl-selenium compounds using copper(I) catalysts UNIVERSITY OF MASSACHUSETTS (US) 2006-09-26 US disclosed
US-7060858-B2 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2006-06-13 US disclosed
EP-1640363-A1 PROCESS FOR PRODUCTION OF MONOSULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, CURABLE COMPOSITIONS, AND PRODUCTS OF CURING San-Apro Limited (JP) 2006-03-29 EP disclosed
US-20040030158-A1 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2004-02-12 US disclosed
EP-1350789-A1 PROCESS FOR PRODUCING SULFONIUM SALT San-Apro Limited (JP) 2003-10-08 EP disclosed
WO-1994018162-A1 PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing RPS6, SPIN4, SRM TSHR 3341/4885ACHE 3338/4885NPC1 4800/4885
US-20040030158-A1 Method for manufacturing sulfonium salts MLX, STS, SULT1A1 TSHR 3172/4885ACHE 4432/4885NPC1 2763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.