SCHEMBL5850317

SCHEMBL5850317

Cc1ccccc1OCC(C)(C)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.67
SSTR4 P31391 4/20 0.53
SSTR1 P30872 1/20 0.53
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
NOTUM Q6P988 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
CYP1A2 P05177 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TTR P02766 1/20 0.47
CYP2C8 P10632 1/20 0.47
CHRM1 P11229 1/20 0.47
ADRA1A P35348 1/20 0.47
PPARG P37231 1/20 0.47
HTR2B P41595 1/20 0.47
PPARA Q07869 1/20 0.47
SLCO1B3 Q9NPD5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11731959 0.85 SSTR4 (0.50) CYP2C9SSTR4SSTR1RXRARXRB
SCHEMBL21748762 0.81 SSTR4 (0.54) CYP2C9SSTR4SSTR1KDM4ETSHR
SCHEMBL21748887 0.81 SSTR4 (0.55) CYP2C9SSTR4SSTR1RXRARXRB
SCHEMBL21748542 0.81 SSTR4 (0.54) CYP2C9SSTR4SSTR1KDM4ETDP1
SCHEMBL5368512 0.81 SSTR1 (0.54) CYP2C9SSTR4SSTR1SMN1; SMN2KDM4E
SCHEMBL24440184 0.81 LMNA (0.52) CYP2C9SMN1; SMN2CYP1A2KDM4ETSHR
SCHEMBL18174935 0.81 CYP2C9 (0.56) CYP2C9SSTR4SSTR1SMN1; SMN2CYP1A2
SCHEMBL21991307 0.80 CYP2C9 (1.00) CYP2C9SMN1; SMN2CYP1A2KDM4ETSHR
SCHEMBL21748603 0.79 SSTR4 (0.56) CYP2C9SSTR4SSTR1RXRARXRB
SCHEMBL5724626 0.78 PPARA (0.58) CYP2C9SSTR4PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7101831-B2 Compositions of material, especially lubricants and pressure transmitting means, the production and use thereof FUCHS PETROLUB AG (DE) 2006-09-05 US claimed
EP-1417287-A1 NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICUALR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF Fuchs Petrolub AG (DE) 2004-05-12 EP claimed
US-20030186823-A1 Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof FUCHS PETROLUB SE (DE) 2003-10-02 US claimed
WO-2001053438-A1 NOVEL COMPOSITIONS OF MATERIAL, ESPECIALLY LUBRICANTS AND PRESSURE TRANSMITTING MEANS, THE PRODUCTION AND USE THEREOF FUCHS PETROLUB AG (DE) 2001-07-26 WO claimed
US-7101831-B2 Compositions of material, especially lubricants and pressure transmitting means, the production and use thereof FUCHS PETROLUB AG (DE) 2006-09-05 US disclosed
EP-1417287-A1 NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICUALR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF Fuchs Petrolub AG (DE) 2004-05-12 EP disclosed
US-20030186823-A1 Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof FUCHS PETROLUB SE (DE) 2003-10-02 US disclosed
WO-2001053438-A1 NOVEL COMPOSITIONS OF MATERIAL, ESPECIALLY LUBRICANTS AND PRESSURE TRANSMITTING MEANS, THE PRODUCTION AND USE THEREOF FUCHS PETROLUB AG (DE) 2001-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186823-A1 Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof SLC27A2, SLC27A1, ELOVL1 CYP2C9 2227/4885SSTR4 4549/4885SSTR1 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.