SCHEMBL610080

SCHEMBL610080

O=C(O)c1cc(NS(=O)(=O)c2ccc([N+](=O)[O-])cc2)ccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
PTPN5 P54829 1/20 0.65
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CA2 P00918 2/20 0.58
CA1 P00915 1/20 0.58
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
TDP1 Q9NUW8 2/20 0.56
KDM4E B2RXH2 1/20 0.56
CYP3A4 P08684 1/20 0.56
HPGD P15428 1/20 0.56
BCL2L1 Q07817 1/20 0.56
MCL1 Q07820 1/20 0.56
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
MAPT P10636 1/20 0.53
HTT P42858 1/20 0.53
ABL1 P00519 1/20 0.53
AKT1 P31749 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390524 1.00 ALDH1A1 (0.65) ALDH1A1PTPN5MEN1KMT2ACA2
SCHEMBL18175045 0.85 ALDH1A1 (0.73) ALDH1A1PTPN5MEN1KMT2AKDM4E
SCHEMBL16366458 0.83 ALDH1A1 (0.75) ALDH1A1PTPN5MEN1KMT2AKDM4E
SCHEMBL5330654 0.79 CA2 (0.69) ALDH1A1MEN1KMT2ACA2CA1
SCHEMBL5022924 0.79 ALDH1A1 (1.00) ALDH1A1PTPN5MEN1KMT2AKDM4E
SCHEMBL3500413 0.79 ALDH1A1 (0.69) ALDH1A1PTPN5MEN1KMT2AMCL1
SCHEMBL16471401 0.79 ALDH1A1 (0.65) ALDH1A1PTPN5MEN1KMT2AKDM4E
SCHEMBL15121254 0.79 PTPN5 (1.00) ALDH1A1PTPN5MEN1KMT2ACA2
SCHEMBL9997138 0.78 PFKFB3 (0.62) ALDH1A1MEN1KMT2ACA2CA12
SCHEMBL9997703 0.78 ALDH1A1 (0.67) ALDH1A1PTPN5MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902536-B1 COMPOSITIONS COMPRISING 5-BENZYLAMINOSALICYLIC ACID COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IN A COMPANION ANIMAL GNT PHARMA CO LTD (KR) 2025-09-03 EP claimed
WO-2023156808-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-08-24 WO claimed
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-07-27 US claimed
US-20220249343-A1 COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF GNT PHARMA CO., LTD. (KR) 2022-08-11 US claimed
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2022-08-04 US claimed
EP-3998058-A1 COSMETIC COMPOSITION COMPRISING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE AND LOCAL ADMINISTRATION METHOD THEREOF GNT Pharma Co., Ltd (KR) 2022-05-18 EP claimed
CN-114096227-A Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2022-02-25 CN claimed
CN-113710242-A Compositions and methods for treating neurodegenerative disorders 吉恩特药业株式会社 2021-11-26 CN claimed
EP-3902536-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT Pharma Co., Ltd (KR) 2021-11-03 EP claimed
WO-2021006637-A1 COSMETIC COMPOSITION COMPRISING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE AND LOCAL ADMINISTRATION METHOD THEREOF 주식회사 지엔티파마 2021-01-14 WO claimed
WO-2020136441-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2020-07-02 WO claimed
US-20120301551-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2012-11-29 US claimed
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2012-02-16 US claimed
US-20070298129-A1 Compounds and compositions for treating neuronal death or neurological dysfunction NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2007-12-27 US claimed
US-20070049565-A1 Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2007-03-01 US claimed
US-6964982-B2 Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system NEUROTECH CO., LTD. (KR) 2005-11-15 US claimed
EP-1274675-B1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING NEURODEGENERATION IN ACUTE AND CHRONIC INJURIES IN THE CENTRAL NERVOUS SYSTEM NEUROTECH CO LTD (KR) 2004-09-01 EP claimed
US-20030045575-A1 Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system NEUROTECH CO., LTD. 2003-03-06 US claimed
EP-1274675-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING NEURODEGENERATION IN ACUTE AND CHRONIC INJURIES IN THE CENTRAL NERVOUS SYSTEM Neurotech Co., Ltd. (KR) 2003-01-15 EP claimed
WO-2001079153-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING NEURODEGENERATION IN ACUTE AND CHRONIC INJURIES IN THE CENTRAL NERVOUS SYSTEM NEUROTECH CO., LTD. (KR) 2001-10-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120301551-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION BCL2, BAX, SMN1; SMN2 ALDH1A1 1961/4885PTPN5 4647/4885MEN1 3939/4885
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS HAO2, ACOX1, HAO1 ALDH1A1 309/4885PTPN5 3142/4885MEN1 4852/4885
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS PRNP, PSEN1, GRIK5 ALDH1A1 859/4885PTPN5 2931/4885MEN1 4216/4885
US-20070298129-A1 Compounds and compositions for treating neuronal death or neurological dysfunction BCL2, BAX, SMN1; SMN2 ALDH1A1 1961/4885PTPN5 4647/4885MEN1 3939/4885
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT HTR5A, HTR6, MC5R ALDH1A1 133/4885PTPN5 1267/4885MEN1 4409/4885
US-20070049565-A1 Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction BAD, MAP1LC3B, XIAP ALDH1A1 2762/4885PTPN5 3455/4885MEN1 3577/4885
US-20220249343-A1 COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF ALOX5, ALOX15, IL5 ALDH1A1 93/4885PTPN5 1259/4885MEN1 4628/4885
US-20030045575-A1 Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system GRIK5, GRIN2A, GRIN2C ALDH1A1 831/4885PTPN5 2527/4885MEN1 4018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.