SCHEMBL181753

SCHEMBL181753

O=C1CS(=O)(=O)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLCG1 P19174 1/20 0.47
MIF P14174 1/20 0.46
GPR3 P46089 1/20 0.46
NOTUM Q6P988 1/20 0.44
VEGFA P15692 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
KMT2A Q03164 3/20 0.42
CA9 Q16790 3/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 2/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
CA1 P00915 1/20 0.42
LMNA P02545 1/20 0.42
BCHE P06276 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2675124 0.78 KMT2A (0.46) PLCG1MIFGPR3TDP1KMT2A
SCHEMBL10196636 0.76 GPR3 (0.44) PLCG1MIFGPR3NOTUMTDP1
SCHEMBL9001235 0.76 NOTUM (0.50) PLCG1MIFGPR3NOTUMTDP1
SCHEMBL6205306 0.75 CYP2A6 (0.47) MIFGPR3TDP1KMT2ACA9
SCHEMBL10159177 0.75 NOTUM (0.46) PLCG1MIFGPR3NOTUMTDP1
SCHEMBL10443136 0.75 MAOA (0.52) PLCG1MIFGPR3NOTUMTDP1
SCHEMBL12746139 0.75 VEGFA (0.47) PLCG1NOTUMVEGFAKMT2ACA9
SCHEMBL10421541 0.72 VEGFA (0.51) PLCG1NOTUMVEGFATDP1KMT2A
SCHEMBL12746149 0.72 VEGFA (0.41) MIFNOTUMVEGFAKMT2AKDM4E
SCHEMBL12746145 0.72 GSTP1 (0.47) MIFNOTUMVEGFAKMT2ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058691-A Multifunctional fluorescent probe responding to sulfur dioxide and polarity 河南财政金融学院 2025-05-30 CN claimed
CN-109053678-B Preparation method of benzo [ b ] thiophene-3 (2H) -ketone-1, 1-dioxide 乐平市科乐化学科技有限公司 2022-05-27 CN claimed
US-6921591-B2 Luminescent device material, luminescent device using the same, and amine compound FUJI PHOTO FILM CO., LTD. (JP) 2005-07-26 US claimed
US-20050065351-A1 Luminescent device material, luminescent device using the same, and amine compound FUJI PHOTO FILM CO., LTD. 2005-03-24 US claimed
US-6776930-B2 POLYMER BONDED TO DYE EASTMAN KODAK COMPANY 2004-08-17 US claimed
EP-0775938-B1 Combination of yellow filter dye and 4-equivalent pyrazolone magenta coupler EASTMAN KODAK CO (US) 2003-02-12 EP claimed
US-6416942-B1 LIGHT SENSITIVE PHOTOGRAPHIC SILVER HALIDE MATERIAL WITH INDOLE COMPOUNDS WITH CARBOXYLIC GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 US claimed
US-20010023938-A1 Polymer bonded to dye ALLEN MAX (US) 2001-09-27 US claimed
US-6197223-B1 REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND EASTMAN CHEMICAL COMPANY 2001-03-06 US claimed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP claimed
US-5459026-A N-phosphonoalkylindole derivatives FUJI PHOTO FILM CO., LTD. (JP) 1995-10-17 US claimed
EP-0605566-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN CHEMICAL COMPANY (US) 1994-07-13 EP claimed
EP-0397435-B1 Near infrared antihalation dyes MINNESOTA MINING & MFG (US) 1994-02-02 EP claimed
US-5213957-A Oxonol dye with carboxy or sulfonamide group and indale ring FUJI PHOTO FILM CO., LTD. (JP) 1993-05-25 US claimed
WO-1993006147-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-04-01 WO claimed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
US-5064747-A Improved photosensitivity using an unsaturated 1,3-dithiol-2-ylidene derivative; lithographic printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US claimed
EP-0430186-A1 Silver halide photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1991-06-05 EP claimed
EP-0410654-A2 Light- sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP claimed
EP-0397435-A1 Near infrared antihalation dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065351-A1 Luminescent device material, luminescent device using the same, and amine compound H1-2, SAT1, CHRM2 PLCG1 4326/4885MIF 3725/4885GPR3 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.