Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17118315 | 0.89 | KIF11 (0.38) | KIF11PTPN5ALDH1A1TSHRCYP2C9 | |
| SCHEMBL15975759 | 0.83 | ALDH1A1 (0.47) | KIF11ALDH1A1 | |
| SCHEMBL3292244 | 0.83 | ALDH1A1 (0.47) | KIF11ALDH1A1 | |
| SCHEMBL2005519 | 0.83 | ALDH1A1 (0.47) | KIF11ALDH1A1 | |
| SCHEMBL11822974 | 0.83 | KIF11 (0.55) | KIF11PTPN5ALDH1A1TSHRCYP2C9 | |
| SCHEMBL18175861 | 0.82 | APP (0.41) | ALDH1A1TSHRNR1H2NR1H3PTPN1 | |
| SCHEMBL21180468 | 0.81 | L3MBTL1 (0.47) | KIF11ALDH1A1PTPN1 | |
| SCHEMBL20806535 | 0.81 | KIF11 (0.59) | KIF11PTPN5ALDH1A1TSHRCYP2C9 | |
| SCHEMBL3889979 | 0.81 | ALDH1A1 (0.53) | KIF11ALDH1A1 | |
| SCHEMBL9319701 | 0.81 | ALDH1A1 (0.53) | KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745113-B1 | NOVEL MATERIAL MIXTURES FOR USE IN ELECTROLUMINESCENCE | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |