Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852502 | 0.85 | TNNI3K (0.50) | TNNI3KKMT2AALDH1A1CYP2C9LMNA | |
| SCHEMBL20888429 | 0.83 | TNNI3K (0.49) | TNNI3KKMT2AALDH1A1CYP2C9LMNA | |
| SCHEMBL922755 | 0.83 | CYP19A1 (0.66) | KMT2AALDH1A1CYP19A1POLBLMNA | |
| SCHEMBL4159966 | 0.80 | LMNA (0.49) | TNNI3KKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27975322 | 0.79 | CA2 (0.61) | KMT2AALDH1A1CYP19A1CYP2C9MAPK1 | |
| SCHEMBL6949807 | 0.79 | CYP2C9 (0.66) | KMT2AALDH1A1CYP2C9POLBLMNA | |
| Diethylamine SCHEMBL3999776 | 0.79 | CYP19A1 (0.60) | KMT2AALDH1A1CYP19A1POLBLMNA | |
| SCHEMBL7258320 | 0.78 | GBA1 (0.62) | KMT2AALDH1A1CYP19A1POLBMEN1 | |
| SCHEMBL11777846 | 0.77 | POLB (0.49) | TNNI3KKMT2ACYP19A1POLBMAPT | |
| SCHEMBL350324 | 0.77 | KMT2A (0.77) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |