Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28250806 | 0.85 | CA12 (0.52) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL12852694 | 0.84 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL67540 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL588343 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL177003 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5178010 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28444399 | 0.79 | KDM4E (0.51) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL18175964 | 0.79 | CA1 (0.48) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL13151172 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5178012 | 0.78 | POLB (0.60) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |