SCHEMBL588343

SCHEMBL588343

COC(=O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
MAPT P10636 2/20 0.62
MEN1 O00255 1/20 0.62
HPGD P15428 1/20 0.62
XBP1 P17861 1/20 0.62
HTT P42858 1/20 0.62
KMT2A Q03164 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA12 O43570 3/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
KDM4E B2RXH2 2/20 0.56
XDH P47989 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67540 0.95 ALDH1A1 (0.62) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL4734613 0.87 ALDH1A1 (0.56) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL30570165 0.87 CNR2 (0.56) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL2159357 0.87 TPMT (0.61) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL8440378 0.87 ALDH1A1 (0.60) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL5185978 0.87 CA12 (0.73) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL16961231 0.87 ALDH1A1 (0.56) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL177003 0.87 ALDH1A1 (0.51) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL30045029 0.87 TPMT (0.61) ALDH1A1MAPTMEN1HPGDXBP1
SCHEMBL8979351 0.87 CNR2 (0.56) ALDH1A1MAPTMEN1HPGDXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565734-A Psoralen ester derivatives and applications thereof 中国科学院新疆理化技术研究所 2017-04-19 CN claimed
EP-4077287-B1 EFFICIENT PROCESS FOR MAKING 6-CARBOXY BENZOXAZOLE DERIVATIVES PFIZER IRELAND PHARMACEUTICALS UNLIMITED COMPANY (IE) 2025-11-19 EP disclosed
EP-3634403-B1 PHENYL-HETEROCYCLE-PHENYL DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF MELANOMA MAX PLANCK GESELLSCHAFT (DE) 2025-06-25 EP disclosed
CN-115135639-B Efficient process for preparing 6-carboxybenzoxazole derivatives 辉瑞爱尔兰制药公司 2025-04-01 CN disclosed
CN-119528704-A Method for preparing 3', 5' -dichloro-2, 2, 2-trifluoro acetophenone 帕潘纳(北京)科技有限公司 2025-02-28 CN disclosed
CN-119390549-A Preparation process of fluororalrana intermediate 重庆普佑生物医药有限公司 2025-02-07 CN disclosed
CN-116535298-B Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone 研峰科技(北京)有限公司 2023-09-22 CN disclosed
CN-116535298-B Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone 研峰科技(北京)有限公司 2023-09-22 CN disclosed
CN-116535298-A Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone 研峰科技(北京)有限公司 2023-08-04 CN disclosed
CN-116535298-A Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone 研峰科技(北京)有限公司 2023-08-04 CN disclosed
US-5886130-A THE CO-POLYMERS ARE USEFUL AS MOLDING RESINS, AND COMPOSITE MATRIX RESINS, AND WHERE AR IS HETEROARYLENE AS ION EXCHANGE RESINS. MAXDEM INCORPORATED (US) 1999-03-23 US disclosed
US-5886210-A Method for preparing aromatic compounds ROHM AND HAAS COMPANY (US) 1999-03-23 US disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed
EP-0825173-A1 Method for preparing aromatic compounds ROHM AND HAAS COMPANY (US) 1998-02-25 EP disclosed
EP-0773249-A1 Polyphenylene co-polymers MAXDEM INCORPORATED (US) 1997-05-14 EP disclosed
EP-0027155-B1 PROCESS FOR DEHYDROHALOGENATING (POLYHALOALKYL)BENZENES THE DOW CHEMICAL COMPANY (US) 1983-08-31 EP disclosed
EP-0027155-A1 Process for dehydrohalogenating (polyhaloalkyl)benzenes THE DOW CHEMICAL COMPANY (US) 1981-04-22 EP disclosed
US-4230642-A Process for producing 3,5-dichloro-α-methylstyrene ISHIHARA SANGYO KAISHA LIMITED (JP) 1980-10-28 US disclosed
US-4205015-A Dehydrohalogenation of (polyhaloalkyl) benzenes with support Lewis acid catalysts THE DOW CHEMICAL COMPANY (US) 1980-05-27 US disclosed
US-4188346-A Dehydrohalogenation of (polyhaloalkyl)benzenes THE DOW CHEMICAL COMPANY (US) 1980-02-12 US disclosed