Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | XBP1 | P17861 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588343 | 0.95 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4734613 | 0.92 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL30045029 | 0.92 | TPMT (0.61) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL16961231 | 0.92 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL2159357 | 0.92 | TPMT (0.61) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL3489722 | 0.90 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL3487770 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL5185978 | 0.87 | CA12 (0.73) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL177003 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8440378 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271158-B | Method for synthesizing deuterium-labeled substance containing deuterium atom structural unit | 山东大学 | 2026-05-12 | — | — | CN | disclosed |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20250115574-A1 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | VIB VZW (BE) | 2025-04-10 | — | — | US | disclosed |
| CN-115872894-B | Synthesis of nonionic contrast agents | 上海慧聚药业有限公司 | 2024-12-24 | — | — | CN | disclosed |
| EP-4452253-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| CN-118271158-A | Method for synthesizing deuterium-labeled substance containing deuterium atom structural unit | 山东大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-115551839-B | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2005108391-A1 | AMIDES AS BACE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-11-17 | — | — | WO | disclosed |
| WO-2005108358-A2 | PYRROLIDINE DERIVATIVES USEFUL AS BACE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-11-17 | — | — | WO | disclosed |
| EP-0855400-B1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL IND LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5880309-A | DIALKYL DIALKOXYCARBONYLPHENYL PHOSPHONATES USEFUL AS RESIN MODIFIERS PRODUCED AT HIGH YIELD AND LOW COST BY HEATING A TRIALKYL PHOSPHITE AND A DIALKOXYCARBONYLPHENYL HALIDE IN THE PRESENCE OF A PALLADIUM OR NICKEL CATALYST AND HYDROLYZING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0855400-A1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| CN-1037602-C | N-acetophenone formamide and application as bactericide agent of same | ROHM & HAAS (US) | 1998-03-04 | — | — | CN | disclosed |
| EP-0604019-B1 | N-Acetonylbenzamides and their use as fungicides | ROHM & HAAS (US) | 1996-05-08 | — | — | EP | disclosed |
| CN-1117961-A | N-acetophenone formamide and application as bactericide agent of same | ROHM & HAAS (US) | 1996-03-06 | — | — | CN | disclosed |
| EP-0604019-A1 | N-Acetonylbenzamides and their use as fungicides | ROHM AND HAAS COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5254584-A | Controlling phytopathogens | ROHM AND HAAS COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | ALDH1A1 1935/4885MAPT 1955/4885MEN1 3883/4885 |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | ALDH1A1 2212/4885MAPT 2994/4885MEN1 4404/4885 |
| US-20250115574-A1 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | ALDH1A1 2212/4885MAPT 2994/4885MEN1 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.