Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763879 | 0.85 | CA5A (0.48) | CA5ALMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20488853 | 0.79 | KDM4E (0.55) | LMNAMAPTTSHRCA2ALDH1A1 | |
| SCHEMBL4927775 | 0.78 | NPC1 (0.43) | CA5ALMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL18266234 | 0.78 | NOS2 (0.50) | CA5ALMNAPRKCISMN1; SMN2NPC1 | |
| SCHEMBL6251916 | 0.76 | CA5A (0.40) | CA5ALMNAPRKCIGABRPGABRD | |
| SCHEMBL26690039 | 0.74 | ALOX15 (0.52) | CA5ALMNASMN1; SMN2MAPTTSHR | |
| SCHEMBL25928593 | 0.73 | CA5A (0.38) | CA5ALMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28223775 | 0.71 | KMT2A (0.39) | HTR6LMNAPRKCISMN1; SMN2NPC1 | |
| SCHEMBL26690129 | 0.71 | KDM4E (0.44) | CA5ALMNASMN1; SMN2MAPTCA2 | |
| SCHEMBL5104318 | 0.70 | GSK3B (0.57) | CA5ALMNAPRKCISMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |