Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819014 | 0.92 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL1820560 | 0.90 | MEN1 (0.44) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL1818746 | 0.90 | MEN1 (0.44) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL2009700 | 0.90 | MEN1 (0.44) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL1819502 | 0.71 | TSHR (0.49) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL1818765 | 0.69 | TSHR (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1815850 | 0.69 | TSHR (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8190977 | 0.69 | ARG1 (0.51) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL8843134 | 0.68 | SMN1; SMN2 (0.56) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL1824226 | 0.67 | TSHR (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498782-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060262-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2011-05-19 | — | — | WO | disclosed |