Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29684657 | 0.92 | TSHR (0.53) | TSHRALDH1A1KDM4EGAACYP2C9 | |
| SCHEMBL28231556 | 0.91 | TSHR (0.56) | TSHRALDH1A1KDM4EGAACYP2C9 | |
| SCHEMBL1726734 | 0.89 | TSHR (0.58) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL29684786 | 0.88 | TSHR (0.50) | TSHRALDH1A1KDM4EGAACYP2C9 | |
| Oxalic Acid SCHEMBL29685154 | 0.85 | TSHR (0.55) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL29684863 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL2435688 | 0.79 | ALDH1A1 (0.54) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL28263344 | 0.75 | TSHR (0.51) | TSHRALDH1A1KDM4ECYP2C9GLA | |
| Gluconic Acid SCHEMBL29684835 | 0.74 | TSHR (0.44) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL1817609 | 0.71 | MEN1 (0.38) | TSHRALDH1A1KDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498782-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060262-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2011-05-19 | — | — | WO | disclosed |