Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309461 | 1.00 | NOS1 (0.42) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL8136255 | 0.89 | NOS1 (0.40) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL28062530 | 0.87 | NOS1 (0.46) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL29224728 | 0.86 | NOS1 (0.42) | NOS1NOS3NOS2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8848963 | 0.85 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL304099 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL31606685 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL304098 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL19858386 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL9952902 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160314241-A1 | DRUG DISCOVERY METHOD | Keddem Bioscience Ltd. (IL) | 2016-10-27 | — | — | US | disclosed |