Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176944 | 0.92 | ADORA2A (0.43) | ADORA2ATMIGD3ADORA1PDE4APDE4B | |
| SCHEMBL18179481 | 0.89 | TMIGD3 (0.41) | ADORA2ATMIGD3ADORA1STK17BSTK17A | |
| SCHEMBL18176935 | 0.89 | TMIGD3 (0.41) | ADORA2ATMIGD3ADORA1PDE4APDE4B | |
| SCHEMBL30254310 | 0.86 | PDE4A (0.40) | ADORA2ATMIGD3ADORA1CCNB2CDK1 | |
| SCHEMBL18176939 | 0.85 | TMIGD3 (0.44) | ADORA2ATMIGD3ADORA1CCNB2CDK1 | |
| SCHEMBL25222870 | 0.85 | CCNE2 (0.42) | ADORA2ATMIGD3ADORA1STK17BSTK17A | |
| SCHEMBL23885300 | 0.85 | TMIGD3 (0.43) | ADORA2ATMIGD3ADORA1STK17BSTK17A | |
| SCHEMBL30052380 | 0.85 | TMIGD3 (0.43) | ADORA2ATMIGD3ADORA1STK17BSTK17A | |
| SCHEMBL18176956 | 0.84 | ADORA2A (0.49) | ADORA2ATMIGD3ADORA1CCNB2CDK1 | |
| SCHEMBL22359200 | 0.79 | ADCY5 (0.57) | ADORA2AADORA1ALDH1A1ADORA2BDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311845-A1 | NUCLEOTIDE DERIVATIVE OR SALT THEREOF, NUCLEOTIDE-DERIVED 5'-PHOSPHATE ESTER OR SALT THEREOF, NUCLEOTIDE-DERIVED 3'-PHOSPHORAMIDITE COMPOUND OR SALT THEREOF, AND POLYNUCLEOTIDE | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311845-A1 | NUCLEOTIDE DERIVATIVE OR SALT THEREOF, NUCLEOTIDE-DERIVED 5'-PHOSPHATE ESTER OR SALT THEREOF, NUCLEOTIDE-DERIVED 3'-PHOSPHORAMIDITE COMPOUND OR SALT THEREOF, AND POLYNUCLEOTIDE | NT5C3B, PNP, NUDT1 | ADORA2A 683/4885TMIGD3 4771/4885ADORA1 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.