Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176940 | 0.89 | ADORA2A (0.48) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL18176944 | 0.89 | ADORA2A (0.43) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL18176935 | 0.87 | TMIGD3 (0.41) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL18176939 | 0.83 | TMIGD3 (0.44) | TMIGD3ADORA2AADORA1BRD4HDAC1 | |
| SCHEMBL25222870 | 0.82 | CCNE2 (0.42) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL30052380 | 0.82 | TMIGD3 (0.43) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL23885300 | 0.82 | TMIGD3 (0.43) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL18179484 | 0.78 | ADORA2A (0.49) | TMIGD3ADORA2AADORA1ADCY5HTT | |
| SCHEMBL30254310 | 0.78 | PDE4A (0.40) | TMIGD3ADORA2AADORA1STK17BSTK17A | |
| SCHEMBL22359200 | 0.77 | ADCY5 (0.57) | ADORA2AADORA1DOT1LADCY5ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311845-A1 | NUCLEOTIDE DERIVATIVE OR SALT THEREOF, NUCLEOTIDE-DERIVED 5'-PHOSPHATE ESTER OR SALT THEREOF, NUCLEOTIDE-DERIVED 3'-PHOSPHORAMIDITE COMPOUND OR SALT THEREOF, AND POLYNUCLEOTIDE | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311845-A1 | NUCLEOTIDE DERIVATIVE OR SALT THEREOF, NUCLEOTIDE-DERIVED 5'-PHOSPHATE ESTER OR SALT THEREOF, NUCLEOTIDE-DERIVED 3'-PHOSPHORAMIDITE COMPOUND OR SALT THEREOF, AND POLYNUCLEOTIDE | NT5C3B, PNP, NUDT1 | TMIGD3 4771/4885ADORA2A 683/4885ADORA1 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.