Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | PKM | P14618 | 4/20 | 1.00 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15213964 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EPKMDDAH1 | |
| SCHEMBL2466643 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EPKMDDAH1 | |
| SCHEMBL16921274 | 0.80 | ALDH1A1 (0.73) | ALDH1A1MAPTKDM4EPKMDDAH1 | |
| SCHEMBL28429884 | 0.80 | ALDH1A1 (0.84) | ALDH1A1MAPTKDM4EPKMDDAH1 | |
| SCHEMBL13680867 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPKMDDAH1 | |
| SCHEMBL1567653 | 0.76 | KDM4E (0.61) | ALDH1A1MAPTKDM4EPKMSMN1; SMN2 | |
| SCHEMBL805155 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EPKMCYP1A2 | |
| SCHEMBL4896906 | 0.74 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EPKMCYP1A2 | |
| SCHEMBL1566761 | 0.74 | FFAR1 (0.73) | ALDH1A1MAPTKDM4EPKMPOLB | |
| SCHEMBL9254121 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EPKMDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | UGDH, G6PD, DPYD | ALDH1A1 54/4885MAPT 2722/4885KDM4E 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.