Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680877 | 0.83 | HTR6 (0.52) | ALDH1A1KDM4EMAPTPKMHTR6 | |
| SCHEMBL13680866 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTPKMHTR6 | |
| SCHEMBL13680982 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTPKMCYP1A2 | |
| SCHEMBL13680868 | 0.81 | PRMT1 (0.49) | ALDH1A1KDM4EMAPTPKMABCB1 | |
| SCHEMBL13680876 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTPKMCYP1A2 | |
| SCHEMBL13680879 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTPKMHTR6 | |
| SCHEMBL13680895 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTPKMHTR6 | |
| SCHEMBL13680883 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTPKMHTR6 | |
| SCHEMBL13680887 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTPKMHTR6 | |
| SCHEMBL13680864 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTPKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |