Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018688 | 0.91 | HPGD (0.58) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL17851134 | 0.86 | L3MBTL1 (0.55) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL13300206 | 0.85 | HPGD (0.59) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL23242464 | 0.85 | KDM4E (0.56) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL21760733 | 0.84 | FOLH1 (0.62) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL13780976 | 0.84 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL13780969 | 0.83 | L3MBTL1 (0.57) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL17850894 | 0.83 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL13780982 | 0.83 | KDM4E (0.52) | KDM4EL3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL29420600 | 0.82 | L3MBTL1 (0.55) | KDM4EL3MBTL1ATMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738627-B2 | Method for synthesizing 2,6-bis[3′-(N-carbazolyl)phenyl]pyridine compound | BEIJING AGLAIA TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2017-08-22 | — | — | US | disclosed |
| US-9738627-B2 | Method for synthesizing 2,6-bis[3′-(N-carbazolyl)phenyl]pyridine compound | BEIJING AGLAIA TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2017-08-22 | — | — | US | disclosed |
| US-20160311799-A1 | METHOD FOR SYNTHESIZING 2,6-BIS[3'-(N-CARBAZOLYL)PHENYL]PYRIDINE COMPOUND | BEIJING AGLAIA TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2016-10-27 | — | — | US | disclosed |
| US-20160311799-A1 | METHOD FOR SYNTHESIZING 2,6-BIS[3'-(N-CARBAZOLYL)PHENYL]PYRIDINE COMPOUND | BEIJING AGLAIA TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311799-A1 | METHOD FOR SYNTHESIZING 2,6-BIS[3'-(N-CARBAZOLYL)PHENYL]PYRIDINE COMPOUND | DHPS, NISCH, PIN4 | KDM4E 1760/4885L3MBTL1 4809/4885ATM 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.