Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30613048 | 0.84 | PIK3CD (0.40) | PIK3CDEGFRERBB2NQO2FECH | |
| SCHEMBL12261810 | 0.84 | ERBB2 (0.45) | KDM4EKMT2AEGFRERBB2NQO2 | |
| SCHEMBL18181595 | 0.84 | TEAD4 (0.38) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL15703717 | 0.82 | CYP2C19 (0.40) | ALDH1A1HPGDKDM4EEGFRERBB2 | |
| SCHEMBL12872519 | 0.81 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL12261806 | 0.75 | ALDH1A1 (0.44) | ALDH1A1RAB9AHPGDNPC1MAPT | |
| SCHEMBL26005853 | 0.75 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL21563376 | 0.75 | PIK3CD (0.47) | ALDH1A1KDM4EPIK3CDEGFRERBB2 | |
| SCHEMBL13185122 | 0.75 | ERBB2 (0.43) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL25177224 | 0.73 | NR4A1 (0.36) | ALDH1A1PIK3CDEGFRERBB2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311780-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RES INC (US) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311780-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | ALDH1A1 684/4885RAB9A 580/4885HPGD 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.