Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360974 | 0.78 | ALDH1A1 (0.84) | KMT2APOLBSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL17007485 | 0.77 | KMT2A (0.62) | KMT2APOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29004530 | 0.77 | POLB (0.76) | KMT2APOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30343311 | 0.77 | POLB (0.76) | KMT2APOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3958348 | 0.76 | KMT2A (0.65) | KMT2APOLBSMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL26258912 | 0.76 | POLB (0.76) | KMT2APOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL18181908 | 0.76 | SMN1; SMN2 (1.00) | KMT2APOLBSMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL18177839 | 0.76 | SMN1; SMN2 (0.74) | KMT2APOLBSMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL5038499 | 0.75 | POLB (0.63) | KMT2APOLBALDH1A1KDM4EPKM | |
| SCHEMBL5068102 | 0.74 | KMT2A (0.59) | KMT2APOLBSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | WASE, NISHIKANT | 2020-03-05 | — | — | US | disclosed |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | NUTECH VENTURES (US) | 2019-07-16 | — | — | US | disclosed |
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | INVITROGEN CORPORATION | 2016-10-27 | — | — | US | disclosed |
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | INVITROGEN CORPORATION | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | KMT2A 2512/4885POLB 3520/4885SMN1; SMN2 4517/4885 |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | FASN, LIPC, SREBF2 | KMT2A 2512/4885POLB 3520/4885SMN1; SMN2 4517/4885 |
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | KMT2A 2512/4885POLB 3520/4885SMN1; SMN2 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.