Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343311 | 1.00 | POLB (0.76) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1617943 | 0.78 | KDM4E (0.62) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL26258912 | 0.77 | POLB (0.76) | POLBALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL30343275 | 0.77 | CYP2D6 (0.68) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL29004533 | 0.77 | CYP2D6 (0.68) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL18177873 | 0.77 | KMT2A (1.00) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL2360974 | 0.76 | ALDH1A1 (0.84) | POLBALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4252561 | 0.76 | MAPT (0.67) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7527409 | 0.75 | POLB (0.72) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL18230449 | 0.75 | KMT2A (0.69) | POLBALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120261-B | Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound | 浙大宁波理工学院 | 2024-01-23 | — | — | CN | disclosed |
| CN-116120261-A | Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound | 浙大宁波理工学院 | 2023-05-16 | — | — | CN | disclosed |