SCHEMBL18177969

SCHEMBL18177969

O=C(Oc1ccccc1)P(=O)(OCF)OCF

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SRC P12931 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPC1 O15118 1/20 0.37
ALOX15 P16050 2/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP19A1 P11511 1/20 0.37
PKM P14618 1/20 0.36
PTK2B Q14289 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563400 0.82 NR1I2 (0.51) MAPTALDH1A1
SCHEMBL4609480 0.81 HTT (0.40) CYP2C9CYP2C19MAPTALDH1A1
SCHEMBL4611213 0.81 TSHR (0.55) SRCNPC1MAPTALDH1A1TSHR
SCHEMBL4610697 0.80 FAAH (0.47) TSHR
SCHEMBL4610119 0.78 ALDH1A1 (0.44) CYP2C9CYP2C19SRCATMTDP1
SCHEMBL4612087 0.78 CYP3A4 (0.42) ATML3MBTL1NPC1ALDH1A1TSHR
SCHEMBL18177963 0.78 FAAH (0.51) ALDH1A1TSHR
Phenyl Diphenoxyphosphinecarboxylate Oxide SCHEMBL4610556 0.77 SRC (0.54) CYP2C9CYP2C19SRCATMTDP1
Phenyl Dimethoxyphosphinecarboxylate Oxide SCHEMBL4610736 0.76 SRC (0.42) CYP2C9CYP2C19SRCATMTDP1
SCHEMBL18182328 0.73 NPC1 (0.47) CYP2C9CYP2C19L3MBTL1NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10374256-B2 Nonaqueous electrolyte solution, electricity storage device using same, and phosphonoformic acid compound used in same UBE INDUSTRIES, LTD. (JP) 2019-08-06 US disclosed
US-20160315351-A1 NONAQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHONOFORMIC ACID COMPOUND USED IN SAME UBE INDUSTRIES, LTD (JP) 2016-10-27 US disclosed
US-20160315351-A1 NONAQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHONOFORMIC ACID COMPOUND USED IN SAME UBE INDUSTRIES, LTD (JP) 2016-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10374256-B2 Nonaqueous electrolyte solution, electricity storage device using same, and phosphonoformic acid compound used in same HCN2, PHOSPHO1, HCN1 CYP2C9 3091/4885CYP2C19 3257/4885SRC 1710/4885
US-20160315351-A1 NONAQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHONOFORMIC ACID COMPOUND USED IN SAME HCN2, PHOSPHO1, HCN1 CYP2C9 3091/4885CYP2C19 3257/4885SRC 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.