Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178457 | 0.90 | RAB9A (0.53) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18178044 | 0.90 | MRGPRX4 (0.52) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18178066 | 0.89 | MRGPRX4 (0.49) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18178071 | 0.88 | MRGPRX4 (0.47) | RAB9AMAPTL3MBTL1MRGPRX4NPC1 | |
| SCHEMBL18178054 | 0.88 | MRGPRX4 (0.51) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18156202 | 0.88 | RORC (0.45) | RAB9AMAPTMRGPRX4RORCNPC1 | |
| SCHEMBL18178109 | 0.87 | L3MBTL1 (0.41) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18178361 | 0.87 | RORC (0.41) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18178119 | 0.86 | MRGPRX4 (0.49) | RAB9AMAPTL3MBTL1ATMMRGPRX4 | |
| SCHEMBL18178047 | 0.86 | MRGPRX4 (0.49) | RAB9AMAPTL3MBTL1ATMMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | RAB9A 1136/4885MAPT 4572/4885L3MBTL1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.