SCHEMBL18179747

SCHEMBL18179747

Cc1cc(Oc2ccc3c(-c4ccccc4C(=O)O)c4ccc(=O)cc-4oc3c2)cc(C)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 5/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
POLB P06746 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ATM Q13315 2/20 0.47
PLEC Q15149 1/20 0.47
CA1 P00915 6/20 0.46
CA2 P00918 6/20 0.46
CA9 Q16790 6/20 0.46
CA12 O43570 4/20 0.46
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
FTO Q9C0B1 2/20 0.44
DNASE1L3 Q13609 1/20 0.43
PRMT1 Q99873 1/20 0.43
ESR1 P03372 1/20 0.42
ABCB1 P08183 1/20 0.42
KDM4E B2RXH2 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18179732 0.90 USP2 (0.56) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL1971500 0.88 USP2 (0.63) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL18179738 0.88 USP2 (0.48) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL1968894 0.85 USP2 (0.65) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL10205417 0.85 USP2 (0.58) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL18179769 0.84 USP2 (0.40) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL18179758 0.84 USP2 (0.40) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL18932154 0.83 USP2 (0.56) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL14527749 0.82 USP2 (0.55) USP2L3MBTL1POLBMEN1KMT2A
SCHEMBL12437910 0.82 USP2 (0.55) USP2L3MBTL1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL VERSITECH LIMITED (HK) 2016-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL HAGH, HADH, FECH USP2 1219/4885L3MBTL1 2301/4885POLB 2612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.