Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205417 | 0.89 | USP2 (0.58) | USP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL14527749 | 0.87 | USP2 (0.55) | USP2L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13609837 | 0.86 | USP2 (0.52) | USP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL23625147 | 0.85 | USP2 (0.55) | USP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL10205413 | 0.85 | PTPN11 (0.54) | USP2L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL31621793 | 0.84 | USP2 (0.55) | USP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL1971500 | 0.84 | USP2 (0.63) | USP2L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL10268461 | 0.84 | USP2 (0.55) | USP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL12437910 | 0.84 | USP2 (0.55) | USP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL1968894 | 0.84 | USP2 (0.65) | USP2L3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210096129-A1 | Methods and Compositions for Spacial and Temporal Measurement of Catalytic Activity | THE UNIVERSITY OF CHICAGO | 2021-04-01 | — | — | US | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | SI, GUSB, ABCG2 | USP2 2543/4885L3MBTL1 2465/4885MEN1 4776/4885 |
| US-20210096129-A1 | Methods and Compositions for Spacial and Temporal Measurement of Catalytic Activity | RNGTT, SCLY, RNASEL | USP2 1614/4885L3MBTL1 1720/4885MEN1 4066/4885 |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | SI, GUSB, ABCG2 | USP2 2543/4885L3MBTL1 2465/4885MEN1 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.