Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836051 | 0.85 | HPGD (0.58) | HPGDKDM4EHSD17B10HTTMTNR1A | |
| SCHEMBL27674000 | 0.84 | ALOX15 (0.46) | HPGDHTTTSHRALDH1A1MEN1 | |
| SCHEMBL7620644 | 0.82 | ALOX15 (0.45) | HPGDKDM4EHSD17B10HTTTSHR | |
| SCHEMBL2791448 | 0.81 | PTGS2 (0.52) | HPGDKDM4EHSD17B10TSHRALDH1A1 | |
| SCHEMBL11709421 | 0.81 | ACHE (0.58) | HPGDKDM4EHSD17B10HTTTSHR | |
| SCHEMBL18050491 | 0.81 | KDM4E (0.53) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL1836742 | 0.81 | KDM4E (0.53) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL11925422 | 0.80 | KDM4E (0.70) | HPGDKDM4EHSD17B10HTTMTNR1A | |
| SCHEMBL6353496 | 0.79 | KDM4E (0.49) | KDM4EMTNR1BTSHRMEN1KMT2A | |
| SCHEMBL11809940 | 0.79 | HPGD (0.51) | HPGDKDM4EHSD17B10HTTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | HPGD 4638/4885KDM4E 2107/4885HSD17B10 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.