Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18183754 | 0.83 | GRM1 (0.37) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL28395307 | 0.81 | GRM1 (0.47) | GRM1CYP11B2TP53CYP3A4MAPK1 | |
| SCHEMBL23349323 | 0.80 | GRM1 (0.35) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL26828839 | 0.80 | GRM1 (0.35) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL9877020 | 0.74 | ACHE (0.41) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL20731174 | 0.74 | ACHE (0.38) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL22575141 | 0.74 | GRM1 (0.34) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL21606986 | 0.74 | ALK (0.34) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL11926935 | 0.74 | ACHE (0.35) | GRM1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL5251667 | 0.74 | USP9X (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724151-B | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-110724151-A | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2020-01-24 | — | — | CN | claimed |
| CN-110724151-B | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110724151-B | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110724151-B | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110724151-A | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-110724151-A | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-110724151-A | Synthesis method of (3, 4-dihydro-2H-pyrano [2,3-b ] pyridine-6-yl) methanol | 成都睿智化学研究有限公司 | 2020-01-24 | — | — | CN | disclosed |
| WO-2016171181-A1 | 2-SUBSTITUTED FUSED PYRAZOLE DERIVATIVES | 大日本住友製薬株式会社 | 2016-10-27 | — | — | WO | disclosed |