Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18186258 | 0.87 | CYP11B1 (0.43) | AAK1HTR2CSLC6A4SLC22A12CYP11B1 | |
| SCHEMBL28241590 | 0.85 | MGLL (0.38) | ALDH1A1HPGDHSD17B10MGLLABHD6 | |
| SCHEMBL31468983 | 0.82 | HTR2C (0.38) | AAK1HTR2CSLC6A4CACNA1GCACNA1B | |
| SCHEMBL16824942 | 0.82 | CYP19A1 (0.43) | ALDH1A1MGLLABHD6CYP11B1CYP11B2 | |
| SCHEMBL18186254 | 0.80 | HTR2C (0.38) | AAK1HTR2CSLC6A4CACNA1GCACNA1B | |
| SCHEMBL8169426 | 0.80 | RIPK1 (0.46) | AAK1HTR2CSLC6A4CACNA1GCACNA1B | |
| SCHEMBL8169606 | 0.80 | SLC6A4 (0.42) | HTR2CSLC6A4CACNA1GCACNA1BCACNA1C | |
| SCHEMBL8164937 | 0.80 | HTR2C (0.38) | AAK1HTR2CSLC6A4CACNA1GCACNA1B | |
| SCHEMBL7246130 | 0.79 | MEN1 (0.42) | ALDH1A1AAK1HTR2CSLC6A4POLB | |
| SCHEMBL28146649 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HPGDHSD17B10MGLLABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106829451-A | A kind of rotary sample introduction mobile device of carbon tetrachloride monitor straight line and its method of work | 徐州工程学院 | 2017-06-13 | — | — | CN | claimed |
| US-9850247-B2 | Pyrimidopyrimidinones useful as Wee-1 kinase inhibitors | ALMAC HOUSE (GB) | 2017-12-26 | — | — | US | disclosed |
| EP-3083625-B1 | PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS | ALMAC DISCOVERY LTD (GB) | 2017-11-01 | — | — | EP | disclosed |
| CN-106829451-A | A kind of rotary sample introduction mobile device of carbon tetrachloride monitor straight line and its method of work | 徐州工程学院 | 2017-06-13 | — | — | CN | disclosed |
| US-20160318936-A1 | PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318936-A1 | PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS | WEE1, WEE2, NME1 | ALDH1A1 1940/4885HPGD 2207/4885HSD17B10 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.