Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL2726810 | 0.93 | TDP1 (0.33) | POLBTSHRALDH1A1FGFR4CHRM2 | |
| Acrylamide SCHEMBL27794838 | 0.90 | TSHR (0.41) | TSHRALDH1A1FGFR4CHRM2CHRM4 | |
| Acrylamide SCHEMBL9145346 | 0.88 | BBOX1 (0.38) | TSHRALDH1A1FGFR4BBOX1 | |
| Acrylamide SCHEMBL27794839 | 0.84 | TSHR (0.42) | TSHRALDH1A1FGFR4CHRM2CHRM4 | |
| SCHEMBL28229885 | 0.84 | POLB (0.35) | POLBTSHRCHRM2CHRM4CHRM5 | |
| Acrylamide SCHEMBL3636541 | 0.84 | TSHR (0.50) | POLBTSHRALDH1A1FGFR4CHRM2 | |
| SCHEMBL2711096 | 0.84 | TDP1 (0.39) | POLBTSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL28224441 | 0.83 | POLB (0.34) | POLBCHRM2CHRM4CHRM5CHRM1 | |
| Acrylamide SCHEMBL27525225 | 0.83 | TSHR (0.41) | TSHRALDH1A1FGFR4CHRM2CHRM4 | |
| Acrylamide SCHEMBL28403516 | 0.82 | TSHR (0.48) | POLBTSHRALDH1A1FGFR4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104119823-A | Adhesive composition, adhesive sheet, surface protective sheet, and optical film | NITTO DENKO CORP | 2014-10-29 | — | — | CN | disclosed |
| US-20120064339-A1 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR SURFACE PROTECTIVE FILMS AND USE THEREOF | NITTO DENKO CORPORATION (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2402408-A1 | ADHESIVE COMPOSITION FOR USE IN SURFACE PROTECTIVE FILM AND USE THEREOF | Nitto Denko Corporation (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-20110206917-A1 | SURFACE PROTECTIVE FILM | NITTO DENKO CORPORATION (JP) | 2011-08-25 | — | — | US | disclosed |
| US-5385802-A | Process for producing toner | FUJI XEROX CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |