Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL181865 | 0.88 | POLB (0.36) | BBOX1ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL4970585 | 0.85 | TSHR (0.46) | BBOX1ALDH1A1TSHRFGFR4 | |
| SCHEMBL27990235 | 0.83 | BBOX1 (0.50) | BBOX1TSHR | |
| Acrylamide SCHEMBL2726810 | 0.81 | TDP1 (0.33) | ALDH1A1TSHRFGFR4 | |
| SCHEMBL28045898 | 0.78 | TSHR (0.44) | BBOX1ALDH1A1TSHR | |
| SCHEMBL27569036 | 0.78 | TSHR (0.40) | ALDH1A1TSHR | |
| Acrylamide SCHEMBL27794838 | 0.77 | TSHR (0.41) | BBOX1ALDH1A1TSHRFGFR4 | |
| SCHEMBL28180741 | 0.77 | ZDHHC20 (0.37) | ALDH1A1TSHR | |
| SCHEMBL6117377 | 0.74 | ZDHHC20 (0.45) | BBOX1ALDH1A1TSHR | |
| Acrylamide SCHEMBL9131270 | 0.74 | ALDH1A1 (0.38) | BBOX1ALDH1A1TSHRFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385802-A | Process for producing toner | FUJI XEROX CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |