Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196843 | 0.70 | RAB9A (0.48) | RAB9ANPC1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL5031002 | 0.69 | MEN1 (0.58) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL5031005 | 0.69 | MEN1 (0.58) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL1609393 | 0.66 | MAPT (0.59) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL1609392 | 0.66 | MAPT (0.59) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL30478655 | 0.64 | MAPT (0.61) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL10384632 | 0.64 | MAPT (0.65) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL1079166 | 0.62 | MAPT (0.68) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29951439 | 0.62 | MAPT (0.68) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL1079165 | 0.62 | MAPT (0.68) | RAB9AMAPTNPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176450-A1 | TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES | PORTLAND STATE UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |