Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190435 | 0.78 | RAB9A (0.58) | RAB9APOLBEPHX2MAPK1KDM4E | |
| SCHEMBL18196846 | 0.75 | RAB9A (0.51) | RAB9APOLBEPHX2MAPK1KDM4E | |
| SCHEMBL18190519 | 0.70 | RAB9A (0.39) | RAB9APOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL2406292 | 0.67 | HDAC1 (0.68) | KDM4EALDH1A1HPGD | |
| SCHEMBL2406289 | 0.67 | HDAC1 (0.68) | KDM4EALDH1A1HPGD | |
| SCHEMBL1623258 | 0.66 | EPHX2 (0.61) | RAB9APOLBEPHX2MAPK1KDM4E | |
| SCHEMBL1609392 | 0.66 | MAPT (0.59) | RAB9AMAPK1NPC1SMN1; SMN2HTT | |
| SCHEMBL1609393 | 0.66 | MAPT (0.59) | RAB9AMAPK1NPC1SMN1; SMN2HTT | |
| SCHEMBL23884376 | 0.65 | ALDH1A1 (0.46) | RAB9APOLBEPHX2MAPK1KDM4E | |
| SCHEMBL3454586 | 0.64 | EPHX2 (0.68) | RAB9AEPHX2MAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176450-A1 | TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES | PORTLAND STATE UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |