Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362042 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL7362044 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL9830039 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL9557207 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL729840 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL2234718 | 0.85 | MME (0.53) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL2234720 | 0.85 | MME (0.53) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL5963397 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL8088657 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL6763914 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1FOLH1SMN1; SMN2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |