Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362042 | 1.00 | ALDH1A1 (0.51) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL7365213 | 0.87 | TAS1R3 (0.46) | FOLH1MME | |
| SCHEMBL7365210 | 0.87 | TAS1R3 (0.46) | FOLH1MME | |
| SCHEMBL18190834 | 0.86 | ALDH1A1 (0.58) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL19651554 | 0.84 | CTSK (0.42) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL19651560 | 0.83 | SMN1; SMN2 (0.44) | MEN1LMNAKMT2AMME | |
| SCHEMBL19651549 | 0.81 | KDM4E (0.41) | MEN1LMNAKMT2AMME | |
| SCHEMBL9830039 | 0.80 | ALDH1A1 (0.58) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL2234720 | 0.80 | MME (0.53) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL2234718 | 0.80 | MME (0.53) | ALDH1A1FOLH1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |