SCHEMBL2234720

SCHEMBL2234720

CC(C)COC(=O)NC(CO)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.53
TGFBR1 P36897 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 2/20 0.40
ITGB3 P05106 1/20 0.40
ITGAV P06756 1/20 0.40
FOLH1 Q04609 6/20 0.40
PLG P00747 1/20 0.38
PLAU P00749 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
TYR P14679 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2234718 1.00 MME (0.53) MMETGFBR1SMN1; SMN2ALDH1A1ITGB3
SCHEMBL18190834 0.85 ALDH1A1 (0.58) MMESMN1; SMN2ALDH1A1FOLH1MEN1
SCHEMBL12514588 0.85 PLG (0.48) MMETGFBR1SMN1; SMN2PLGPLAU
SCHEMBL2236885 0.84 SMN1; SMN2 (0.49) MMESMN1; SMN2ALDH1A1ITGB3ITGAV
SCHEMBL8088657 0.84 SMN1; SMN2 (0.49) MMESMN1; SMN2ALDH1A1ITGB3ITGAV
SCHEMBL2236878 0.84 SMN1; SMN2 (0.49) MMESMN1; SMN2ALDH1A1ITGB3ITGAV
SCHEMBL6763914 0.84 SMN1; SMN2 (0.53) MMESMN1; SMN2ALDH1A1ITGB3ITGAV
SCHEMBL4756588 0.83 TGFBR1 (0.45) MMETGFBR1SMN1; SMN2FOLH1
Hydrochloric Acid SCHEMBL7652855 0.82 SMN1; SMN2 (0.47) MMESMN1; SMN2ALDH1A1ITGB3ITGAV
SCHEMBL17224588 0.81 TGFBR1 (0.53) MMETGFBR1SMN1; SMN2ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130041180-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES PRIVATE LIMITED (IN) 2013-02-14 US claimed
EP-2534127-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN Laboratories Limited (IN) 2012-12-19 EP claimed
WO-2011099033-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES LIMITED (IN) 2011-08-18 WO claimed
US-8907132-B2 Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide MSN LABORATORIES PRIVATE LIMITED (IN) 2014-12-09 US disclosed
US-20130041180-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES PRIVATE LIMITED (IN) 2013-02-14 US disclosed
EP-2534127-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN Laboratories Limited (IN) 2012-12-19 EP disclosed
WO-2011099033-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES LIMITED (IN) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041180-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE AMY1A, PTMA, NAAA MME 306/4885TGFBR1 2124/4885SMN1; SMN2 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.