Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 3/20 | 0.40 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674430 | 0.92 | SLC18A2 (0.42) | SLC18A2GHSRSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11197335 | 0.79 | GAA (0.38) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL3094860 | 0.79 | SLC18A2 (0.34) | SLC18A2 | |
| SCHEMBL4755941 | 0.79 | SLC18A2 (0.35) | SLC18A2 | |
| SCHEMBL5835274 | 0.77 | GHSR (0.65) | GHSRALDH1A1KDM4ELMNA | |
| SCHEMBL7621080 | 0.76 | CXCR5 (0.35) | SLC18A2SMN1; SMN2TSHRKDM4ERAB9A | |
| SCHEMBL11602809 | 0.75 | CTSL (0.37) | SLC18A2ALDH1A1 | |
| SCHEMBL753927 | 0.74 | FFAR3 (0.35) | SLC18A2MAPT | |
| SCHEMBL23956970 | 0.74 | TSHR (0.38) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL2722735 | 0.74 | EPHX1 (0.44) | ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |