SCHEMBL7621080

SCHEMBL7621080

CC(C)OC(=O)NC1(C(=O)O)CC1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 3/20 0.35
IDO1 P14902 1/20 0.35
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 2/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
SLC18A2 Q05940 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15113640 0.82 IDO1 (0.34) IDO1TSHRKDM4EHPGDNPC1
SCHEMBL15116889 0.80 FABP4 (0.31)
SCHEMBL3098003 0.80 SLC18A2 (0.30) SLC18A2
SCHEMBL753927 0.79 FFAR3 (0.35) CXCR5SLC18A2FFAR3
SCHEMBL3101620 0.78 CXCR5 (0.31) CXCR5
SCHEMBL3099215 0.78
SCHEMBL11603044 0.77 FAAH (0.35) SLC18A2
SCHEMBL3098440 0.77 MMP1 (0.40) SLC18A2
SCHEMBL20789220 0.76 IDO1 (0.41) IDO1TSHRKDM4EHPGDALOX15
SCHEMBL18190864 0.76 SLC18A2 (0.40) TSHRKDM4ERAB9ASMN1; SMN2SLC18A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6441044-B1 CROP PROTECTION AGENT BASF AKTIENGESELLSCHAFT (DE) 2002-08-27 US disclosed
EP-0990642-A1 Cycloalkylcarboxamides, their preparation and their use as fungicides BASF AKTIENGESELLSCHAFT (DE) 2000-04-05 EP disclosed