Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961573 | 0.81 | TSHR (0.43) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| SCHEMBL7129369 | 0.81 | TSHR (0.39) | TSHRACHESIGMAR1LMNAALDH1A1 | |
| SCHEMBL2093822 | 0.81 | TSHR (0.39) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| SCHEMBL29239 | 0.76 | TSHR (0.50) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| SCHEMBL29435133 | 0.76 | TSHR (0.50) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| SCHEMBL2620728 | 0.76 | ACHE (0.50) | TSHRACHESIGMAR1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6421167 | 0.74 | TSHR (0.47) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| SCHEMBL21065735 | 0.74 | TSHR (0.47) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL2869837 | 0.74 | TSHR (0.47) | TSHRACHESIGMAR1HSD17B1HSD17B2 | |
| Lithium Ion SCHEMBL19732623 | 0.74 | TSHR (0.47) | TSHRACHESIGMAR1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |