Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190894 | 0.81 | TSHR (0.43) | TSHRACHESIGMAR1LMNASLC6A2 | |
| SCHEMBL7961573 | 0.77 | TSHR (0.43) | TSHRACHESIGMAR1LMNASLC6A2 | |
| SCHEMBL2093822 | 0.77 | TSHR (0.39) | TSHRACHESIGMAR1LMNACYP3A4 | |
| SCHEMBL6606508 | 0.73 | MEN1 (0.42) | TSHRSIGMAR1LMNACYP3A4ALDH1A1 | |
| SCHEMBL25101321 | 0.72 | MAOA (0.44) | TSHRLMNACYP3A4ALDH1A1KDM4E | |
| SCHEMBL2620728 | 0.72 | ACHE (0.50) | TSHRACHESIGMAR1LMNASLC6A2 | |
| SCHEMBL29435133 | 0.72 | TSHR (0.50) | TSHRACHESIGMAR1LMNASLC6A2 | |
| SCHEMBL29239 | 0.72 | TSHR (0.50) | TSHRACHESIGMAR1LMNASLC6A2 | |
| SCHEMBL6563222 | 0.71 | SIGMAR1 (0.45) | SIGMAR1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2869837 | 0.70 | TSHR (0.47) | TSHRACHESIGMAR1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664408-B2 | Contacting a polyoxometalate and an amine in the presence of a diimide | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2003-12-16 | — | — | US | disclosed |
| US-20020165405-A1 | Process for preparing organically-substituted polyoxometalates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165405-A1 | Process for preparing organically-substituted polyoxometalates | TET2, ALKBH3, FTO | TSHR 4832/4885ACHE 611/4885SIGMAR1 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.