SCHEMBL1819296

SCHEMBL1819296

Cc1cc(C(c2ccccc2)(n2cccn2)C(F)(F)F)cc(C)c1N

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.39
KCNA3 P22001 1/20 0.39
POLB P06746 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3434620 0.81 LMNA (0.35) KCNN4KCNA3POLB
SCHEMBL2259159 0.79 POLB (0.35) KCNN4KCNA3POLB
SCHEMBL1822454 0.78 KCNN4 (0.33) KCNN4KCNA3
SCHEMBL1829650 0.77 KCNN4 (0.42) KCNN4KCNA3
SCHEMBL2259111 0.77 POLB (0.38) KCNN4KCNA3POLB
SCHEMBL2260969 0.70 KCNN4 (0.34) KCNN4KCNA3POLB
SCHEMBL7219595 0.66 KCNN4 (0.51) KCNN4KCNA3POLB
SCHEMBL1813640 0.65 NR1H2 (0.43) POLBKIF11
SCHEMBL2392374 0.65 KCNN4 (0.69) KCNN4KCNA3
SCHEMBL23995584 0.65 KCNN4 (0.68) KCNN4KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201603-A1 Novel Acylaminobenzamide Derivatives BAYER CROPSCIENCE AG (DE) 2011-08-18 US disclosed
EP-2318358-A2 ACYLAMINOBENZAMIDE DERIVATIVES Bayer CropScience AG (DE) 2011-05-11 EP disclosed
WO-2010015355-A2 NOVEL ACYLAMINOBENZAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201603-A1 Novel Acylaminobenzamide Derivatives KCNB1, KCNA5, KCNA7 KCNN4 430/4885KCNA3 6/4885POLB 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.