⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15144338 | 1.00 | — | — | |
| SCHEMBL5388376 | 0.78 | — | — | |
| SCHEMBL325666 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL7932456 | 0.76 | — | — | |
| SCHEMBL346677 | 0.76 | — | — | |
| SCHEMBL25379957 | 0.74 | — | — | |
| SCHEMBL6655420 | 0.74 | — | — | |
| SCHEMBL18196807 | 0.73 | GRIK1 (0.30) | — | |
| SCHEMBL10375800 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL13377790 | 0.70 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988351-B2 | Method for producing 5-hydroxypiperidine-2-carboxylic acid | API CORPORATION (JP) | 2018-06-05 | — | — | US | disclosed |
| US-20180002286-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API CORPORATION (JP) | 2018-01-04 | — | — | US | disclosed |
| US-9790181-B2 | Method for producing 5-hydroxypiperidine-2-carboxylic acid | API CORPORATION (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20160318867-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |