⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932456 | 0.81 | — | — | |
| SCHEMBL15144338 | 0.78 | — | — | |
| SCHEMBL8927188 | 0.78 | DNM1 (0.36) | — | |
| SCHEMBL18194363 | 0.78 | — | — | |
| SCHEMBL267594 | 0.75 | PRKCA (0.34) | — | |
| SCHEMBL9848963 | 0.75 | PRKCA (0.34) | — | |
| SCHEMBL8357678 | 0.73 | — | — | |
| SCHEMBL19546012 | 0.73 | PRKCA (0.33) | — | |
| SCHEMBL496590 | 0.73 | — | — | |
| SCHEMBL8357677 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309799-B2 | Methods for the synthesis of milnacipran and congeners thereof | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-20050282898-A1 | Methods for the synthesis of milnacipran and congeners thereof | COLLEGIUM PHARMACEUTICAL (US) | 2005-12-22 | — | — | US | disclosed |
| WO-2005118564-A2 | METHODS FOR THE SYNTHESIS OF MILNACIPRAN AND CONGENERS THEREOF | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20030072716-A1 | Renewable, carbohydrate based CO2-philes | POOVATHINTHODIYIL RAVEENDRAN (US) | 2003-04-17 | — | — | US | disclosed |
| WO-2003000192-A2 | RENEWABLE, CARBOHYDRATE BASED CO2-PHILES | POOVATHINTHODIYIL RAVEENDRAN (US) | 2003-01-03 | — | — | WO | disclosed |
| US-5817590-A | METALLOCENE, IONIZING IONIC COMPOUND, ORGANOALUMINUM COMPOUND, LEWIS BASE | TOSOH CORPORATION (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0648786-B1 | Process for producing alpha-olefin polymer | TOSOH CORP (JP) | 1997-07-16 | — | — | EP | disclosed |
| EP-0619326-B1 | Olefin polymerization catalyst and olefin polymerisation process | TOSOH CORP (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5576259-A | POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE | TOSOH CORPORATION (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0648786-A1 | Process for producing alpha-olefin polymer | Tosoh Corporation (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0052931-A1 | Novel group VA ylides and process for preparing same | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-06-02 | — | — | EP | disclosed |
| EP-0052930-A1 | Novel group VA salts and process for preparing same | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-06-02 | — | — | EP | disclosed |
| EP-0046331-A2 | Nickel ylides | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0046329-A1 | Process for the oligomerization of ethylene | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0046328-A1 | Process for the oligomerization of ethylene in methanol | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0046332-A2 | Process for the preparation of nickel ylides containing ylide ligands with a sulfonated group V component | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4310716-A | NICKEL YLIDE CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4301318-A | OBTAINED BY REACTING ETHYLENE USING A NICKEL YLIDE CATALYST; SOLVENT EXTRACTION OF CATALYST USING AMMONIUM HYDROXIDE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4293727-A | CATALYSIS WITH NICKEL YLIDE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293502-A | CATALYST FOR OLIGOMERIZATION OF ETHYLENE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1981-10-06 | — | — | US | disclosed |