Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015859 | 0.85 | LMNA (0.58) | LMNATHRB | |
| SCHEMBL18203582 | 0.83 | LMNA (0.44) | LMNAMAPK1 | |
| SCHEMBL21023232 | 0.79 | LMNA (0.41) | LMNAMAPK1 | |
| SCHEMBL18187437 | 0.79 | LMNA (0.41) | LMNAMAPK1 | |
| SCHEMBL14001310 | 0.77 | LMNA (0.48) | LMNATHRB | |
| SCHEMBL10625732 | 0.77 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL29130329 | 0.77 | LMNA (0.38) | LMNA | |
| SCHEMBL29130330 | 0.77 | LMNA (0.38) | LMNA | |
| SCHEMBL27064 | 0.74 | LMNA (0.73) | LMNATHRB | |
| SCHEMBL21022968 | 0.74 | MGAM (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988351-B2 | Method for producing 5-hydroxypiperidine-2-carboxylic acid | API CORPORATION (JP) | 2018-06-05 | — | — | US | disclosed |
| US-20180002286-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API CORPORATION (JP) | 2018-01-04 | — | — | US | disclosed |
| US-9790181-B2 | Method for producing 5-hydroxypiperidine-2-carboxylic acid | API CORPORATION (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20160318867-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002286-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | HPD, ADCY5, CYP2A7 | LMNA 2796/4885MAPK1 3375/4885THRB 2245/4885 |
| US-20160318867-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | HPD, ADCY5, CYP2A7 | LMNA 2773/4885MAPK1 3496/4885THRB 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.