Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196133 | 1.00 | MGAM (0.36) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL29130329 | 0.83 | LMNA (0.38) | LMNACYP1A2 | |
| SCHEMBL29130330 | 0.83 | LMNA (0.38) | LMNACYP1A2 | |
| SCHEMBL1107605 | 0.77 | LMNA (0.38) | LMNAALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL9656160 | 0.76 | ALDH1A1 (0.41) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL28479927 | 0.75 | MGAM (0.38) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL28479929 | 0.75 | MGAM (0.38) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL18194367 | 0.74 | LMNA (0.48) | LMNA | |
| SCHEMBL10697367 | 0.73 | GAA (0.43) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL18194372 | 0.73 | MMP8 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091002-B1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API CORP (JP) | 2019-10-09 | — | — | EP | disclosed |
| EP-3486232-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API Corporation (JP) | 2019-05-22 | — | — | EP | disclosed |