Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL5781731 | 1.00 | TSHR (0.47) | TSHRTHRBOPRM1LMNADNM1 | |
| Hexane SCHEMBL7374893 | 1.00 | TSHR (0.47) | TSHRTHRBOPRM1LMNADNM1 | |
| Heptane SCHEMBL7498469 | 0.97 | TSHR (0.53) | TSHRTHRBOPRM1LMNADNM1 | |
| Octane SCHEMBL9190082 | 0.97 | TSHR (0.53) | TSHRTHRBOPRM1LMNADNM1 | |
| Heptane SCHEMBL788860 | 0.97 | TSHR (0.53) | TSHRTHRBOPRM1LMNADNM1 | |
| Pentane SCHEMBL518171 | 0.93 | TSHR (0.50) | TSHRTHRBOPRM1LMNADNM1 | |
| Hexane SCHEMBL2125827 | 0.91 | TSHR (0.39) | TSHRTHRBOPRM1LMNADNM1 | |
| Hexane SCHEMBL9455882 | 0.91 | TSHR (0.43) | TSHRTHRBOPRM1LMNADNM1 | |
| Hexane SCHEMBL9205162 | 0.91 | TSHR (0.39) | TSHRTHRBOPRM1LMNASMN1; SMN2 | |
| Hexane SCHEMBL27772646 | 0.91 | SMN1; SMN2 (0.45) | TSHRTHRBOPRM1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159529-A | Pharmaceutically acceptable salts and crystal forms of fused pyridine ring derivatives and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| CN-115448969-B | Refining method of desogestrel | 上海格苓凯生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-11958798-B2 | Process for the preparation of iloprost | EUROAPI HUNGARY LIMITED LIABILITY COMPANY (HU) | 2024-04-16 | — | — | US | disclosed |
| WO-2024048519-A1 | PYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 | 2024-03-07 | — | — | WO | disclosed |
| US-20240042045-A1 | NANOPARTICLES CONTAINING MULTIPLE CLEAVABLE PRODUGS FOR CANCER THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-08 | — | — | US | disclosed |
| US-20230373932-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-20230373947-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | MITSUI CHEMICALS, INC. (JP) | 2023-11-23 | — | — | US | disclosed |
| CN-117098759-A | Heterocyclic compounds and their use | 组合化学工业株式会社 | 2023-11-21 | — | — | CN | disclosed |
| US-11760742-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
| EP-0001873-A1 | Method of producing polyisoprenoid compounds by carbon-carbon bond formation | Takeda Chemical Industries, Ltd. (JP) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001854-A2 | Process for separating unsaturated and saturated fatty acid esters | THE PROCTER & GAMBLE COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |
| EP-0000322-A1 | Compounds having an anti-depressive or tranquilizing activity, pharmaceutical compositions containing them, and processes and intermediates for their preparation | Astra Läkemedel Aktiebolag (SE) | 1979-01-10 | — | — | EP | disclosed |
| US-4111989-A | N-Substituted alkanesulfenyl-N-alkyl and N-substituted alkanethio-sulfenyl-N-alkyl carbamoyl halide compounds | UNION CARBIDE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4093814-A | CARDIOVASCULAR DISORDERS | E. R. SQUIBB & SONS, INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4080469-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4058549-A | N-substituted cyanoalkane-sulfenyl (and thiosulfenyl)-N-alkyl carbamoyl halides | UNION CARBIDE CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-4048231-A | TREATMENT OF CARDIOVASCULAR DISORDERS | E. R. SQUIBB & SONS, INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4045574-A | ANESTHETICS, CNS DEPRESSANTS | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |
| US-3989724-A | Tetrahydropyran-2-ols | HOFFMANN-LA ROCHE INC. (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | TSHR 3454/4885THRB 3578/4885OPRM1 4010/4885 |
| US-20230373947-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | DDT, CYP4B1, CYP2E1 | TSHR 2017/4885THRB 2069/4885OPRM1 2471/4885 |
| US-20230373932-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | REN, PKD2, ALPI | TSHR 4131/4885THRB 4255/4885OPRM1 457/4885 |
| US-20240042045-A1 | NANOPARTICLES CONTAINING MULTIPLE CLEAVABLE PRODUGS FOR CANCER THERAPY | LDLR, LRP6, LIPG | TSHR 2944/4885THRB 2931/4885OPRM1 613/4885 |
| US-11760742-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | DDT, CYP4B1, CYP2E1 | TSHR 2017/4885THRB 2069/4885OPRM1 2471/4885 |
| US-11958798-B2 | Process for the preparation of iloprost | PTGIS, PTGER1, PTGIR | TSHR 1427/4885THRB 2927/4885OPRM1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.